Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery

Abstract Introduction Postoperative morbidity and le boudoir de luna cognac mortality in patients undergoing major emergency gastrointestinal surgery are a major burden on healthcare systems.Optimal management of perioperative intravenous fluids may reduce mortality rates and improve outcomes from surgery.Previous small trials of cardiac-output gui

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